Etiology of Mental Retardation

Fragile X syndrome: a common etiology of mental retardation.

Fragile X syndrome, second only to Down syndrome among etiologies of mental retardation, was discussed. Clinical, intellectual, and anthropometric characteristics from 67 fragile X positive males, 35 fragile X positive females, and 27 obligate carriers among 29 families was presented. Regression analysis showed little correlation between level of intellect and frequency of fragile sites. The me...

A survey of patients with mental retardation of unknown origin

Introduction: Fragile X syndrome (FXS) is one of the most prevalent genetic causes of developmental disability, representing the most frequent form of inherited severe cognitive deficit. The present study was undertaken to investigate FXS and its prevalence in moderate mentally retarded people in patients. Materials and methods: Nineteen people with moderate mental retardation (MR) who wer...

Mental Retardation

This small book is the first of a series of occasional papers which are to be published under the auspices of the Institute for Research into Mental Retardation, and its author is the chairman of the Institute's Research Committee. In the preface, it is said to be aimed at an intelligent lay audience and it is suggested that 'it will be read with interest and profit by workers in the field of m...

Mental Retardation

title. A book on molecular pharmacology should be concerned primarily with drug-receptor interactions in terms of small molecule-biopolymer interactions. Yet, this text discusses neither protein structure nor nucleic acid structure and minimizes discussions of drug induced conformational changes. In other words, this volume is a good textbook of nonmolecular pharmacology. In the introduction th...

Mental Retardation